[8][9][10] The Soyuz rocket family is one of the most dependable and widely utilized launch vehicles in the history of space travel.

Its earliest form was intended to travel to the Moon without employing a huge booster like the Saturn V or the Soviet N-1 by repeatedly docking with upper stages that had been put in orbit using the same rocket as the Soyuz.

Zond 5 did circle the Moon in September 1968, with two tortoises and other life forms, and returned safely to Earth although in an atmospheric entry which probably would have killed human travelers.

The Progress series of robotic cargo ships for the Salyut, Mir, and ISS use the engine section, orbital module, automatic navigation, docking mechanism, and overall layout of the Soyuz spacecraft, but are incapable of reentry.

While not a direct derivative, the Chinese Shenzhou spacecraft follows the basic template originally pioneered by Soyuz.