Spafford is a town in Onondaga County, New York, United States.

The town was named after Horatio Gates Spafford, a writer and founder of the local library.

Spafford is in the southwestern corner of Onondaga County and is southwest of Syracuse.

Spafford's high terrain, between two of the Finger Lakes, provides spectacular scenery.

Spafford is largely rural, with only small hamlets, and retains many forested areas, some protected as public preserves.

Although situated in a remote corner of Onondaga County, somewhat isolated by two of the Finger Lakes, residential development is expanding into the town from adjacent Skaneateles.