The stations, which were owned and operated by Charter Communications through its acquisition of Time Warner Cable in May 2016, were available in Rochester, Binghamton, Syracuse and Buffalo.

Also in December 2006, Time Warner SportsNet (TWSN) was established by Time Warner Cable in Rochester by acquiring rights to teams owned by the Rochester Sports Group: namely the Americans (ice hockey), Knighthawks (indoor lacrosse), Rattlers (outdoor lacrosse) and Raging Rhinos (soccer).

The channel serves the entire Greater Rochester area, including the Finger Lakes region and Genesee County (Batavia).

Time Warner Cable established a Buffalo version of TWSN on November 19, 2007, on channel 13 on Buffalo-area TWC systems, operating out of the former Empire studios on Indian Church Road in West Seneca.

Locally originated programming mostly ended in June; the network waited until October to cease operations to fulfill its commitment to professional baseball coverage.

Most first-choice Big East basketball and football games produced by ESPN Plus aired exclusively on Time Warner Cable SportsChannel in its broadcast territory, including any that involve Syracuse University.