It occupies a former Brooke Bond tea packing factory in the Spike Island neighbourhood.
The centre also hosts students from the University of the West of England (UWE Bristol) Fine Art and Curating courses.
[2] While individual artists set up their own studios, Bristol Printmakers established an open-plan space where Artspace members could freely use the printing presses and other equipment.
[3][4] In 2007, it began renting out space in the building as co-working and business incubator space to creative professionals and businesses, initially under the Spike Design brand and, since 2021, under the Spike Island Workspace brand.
Exhibiting artists have included Veronica Ryan, Denzil Forrester, Pacita Abad, Andy Holden, David Batchelor, Ivan Seal, Richard Long, Corita Kent and Ciara Phillips, Howardena Pindell, Young In Hong, Lawrence Abu Hamdan and Tanoa Sasraku.