Spiro Crne (Serbian Cyrillic: Спиро Црне; died 22 April 1881) was a rebel leader active in Ottoman Macedonia (in the Kosovo Vilayet).

[1] At that time, the French and German consuls at Salonica were assassinated for their protection of Christian girls who were to be forcefully converted into Islam.

[1] Spiro Crne began to contemplate taking up arms and either deal with the oppressors in his home region by himself or cross into Serbia, and from there join up with friends and countrymen and then attack the Turks.

[2] He was aware that Dime Šike and Timijon Fotić from the Prilep region, who had more than a year earlier captured an Ottoman state postage center with a large sum of money, were living in Vranje.

[3] Spiro Crne was most irritated by the insults received by his sister from Rustem, another libertine in Prilep, while she was on her way to take water from a fountain on Easter.

[3] Resentful against the urban Turks, and already tested in the frequent conflicts with koldžije (guards) of tobacco merchants and zaptiye (gendarmerie), Spiro sought to have a word with Rustem, but he couldn't find him.

[3] At this time, Petar Ristić from Krivogaštani had already left for the mountains, while Spiro's friends, Tode Bačvar, Dime Cincarin, and Pecko Bale arrived.

[3] In a heavy clash with Turks in the surroundings of Kruševo, Petar fell and Spiro was wounded in the arm, managing to flee with his four comrades.

[5] The rumours of the Serbian government's arming of former volunteers reached Prilep, and Spiro Crne and two of his comrades crossed into Serbia.

[4] As more of these rebel bands from Serbia appeared, in that way also the Ottoman government, and privately organized Turks and Albanians, became more active, with harassment of Christians on the right side of the Vardar.

[6] As a result of this pressure, at the beginning of 1880, some 65 rebel leaders (glavari), from almost all provinces in southern Old Serbia and Macedonia, sent an appeal to M. S. Milojević, the former commander of volunteers in the Serbian-Ottoman War (1876–78), asking him to, with requesting from the Serbian government, prepare 1,000 rifles and ammunition for them, and that Milojević is appointed the commander of the rebels and that they are allowed to cross the border and start the rebellion.

[10] At Vranje, he awaited the Serbian government's decision for a general crossing of the border; it was believed that action in Old Serbia and Macedonia was planned in greater style.

[8] Dufski sought that as many rebels as possible are escorted into Ottoman territory, that the Serb people be liberated from atrocities and rallied to arms.

[8] The Ottoman government intercepted some of these contacts, issuing search warrants on many, and imprisoned and condemned a few Christians, such as Pop-Avram, Josif Damjan-Petrović, Rista Novev Kravac and others.

[13] As part of the intervention, Spiro Crne was forced to leave Serbian territory, thus, in April 1881, he and eight comrades left Vranje where they had up until then received support from the government.

[14] After some days, on 22 April, Spiro's band were caught in an ambush,[14] and came into conflict with a heavy Ottoman pursuit on Kozjak, and was destroyed.