Spithridates (Old Persian: *Spiθradātaʰ; Ancient Greek: Σπιθριδάτης Spithridátēs; fl.

365–334 BC) was a Persian satrap of Lydia and Ionia under the high king Darius III Codomannus.

In this engagement, while he was aiming a blow from behind at Alexander the Great, his arm was cut off by Cleitus the Black and he subsequently died.

[1] Diodorus calls him Spithrobates (Σπιθροβάτης Spithrobátēs), and appears to confound him with Mithridates, the son-in-law of Darius, whom Alexander slew in the battle with his own hand; while what Arrian records of Spithridates, Diodorus accounts it for his brother Rhosaces.

[2][3] Spithridates was replaced by the Hellenistic satrap Asander in his territories.