It is generally considered a Biosafety Risk Group 1 fungus;[1] however isolates of S. salmonicolor have been recovered from cerebrospinal fluid, infected skin, a nasal polyp, lymphadenitis and a case of endophthalmitis.

[6] Ballistoconidia are borne from slender extensions of the cell known as sterigmata and are forcibly ejected into the air upon maturity.

[6] Levels of airborne yeast cells peak during the night and are abundant in areas of decaying leaves and grains.

[6] They recognized that the yeast phase produced by Sporobolomyces exhibited the same forcible discharge mechanism as the basidiospores of the Basidiomycota.

[6] The teleomorph presented basidiomycetous traits such as the presence of dikaryotic hyphae with clamp connections and the formation of resting spores known as teliospores.

[6] Sporobolomyces salmonicolor is distinguished from S. johnsonii by the absence in the former of assimilation of maltose, methyl-a-D-glucoside, cellobiose or salicin.

[6] Induction of the sexual stage begins with anastomosis of compatible yeast cells to form dikaryotic hyphae with clamp connections.

[6] Diazonium blue B is a technique used to classify asexual yeasts as members of the Zygomycota, Basidiomycota or Ascomycota.

[6] Colonies grow in the presence of glucose, sucrose, maltose, cellobiose, α,α-trehalose, melezitose, D-arabinose, ethanol, glycerol, D-mannitol, D-glucitol, D-gluconate, succinate, nitrate and urease.

It has been isolated from many areas across the world including Europe, North and South America, Asia, Africa and Antarctica where it is known from a broad spectrum of substrates.

[6][12] It is principally characterized as a phyllosphere fungus and is commonly found in areas of decaying organic material such as leaves and grains as well as ripening grapes.

The most efficient way to avoid exposure in the home is to eliminate moisture sources and keep bathrooms clean, dry and ventilated.

[1] Sporobolomyces salmonicolor has been associated with nasal polyps, lymphadenitis, bone marrow involvement in AIDS patients, infected skin, pseudomeningitis and a case of endophthalmitis.

[2][3][5] S. salmonicolor is also considered a type 1 allergen and has been known to cause asthma, nosocomial allergic alveolitis, and rhinitis.

[3] Exposure to mould and yeast within a military hospital in Finland lead to an outbreak of asthma, alveolitis and rhinitis.

After performing inhalation provocation tests, four cases of asthma caused by Sporobolomyces salmonicolor were reported.

[16] Sporobolomyces salmonicolor was recovered from the cerebrospinal fluid (CSF) of three patients in a hospital, one of whom was a kidney transplant recipient.

[5] The genus Sporobolomyces was the unexpected subject of a poem, The Sporobolomycetologist, with an accompanying musical score, written by the eccentric Canadian mycologist Arthur Henry Reginald Buller.