Sporothrix brasiliensis

However disease has quickly spread to other parts of Brazil and neighboring countries in South America with reported cases in Argentina, Paraguay, Bolivia, Columbia and Panama.

[6] The fungus has been isolated from intestinal and feline fecal samples which suggest that feces from infected cats may contaminate soil and contribute to the spread of the disease.

[7] Sporotrichosis is traditionally associated with subcutaneous exposure of Sporothrix propagules typically through minor injury while coming in contact with plants, soil, or organic matter.

[8] It is believed that S.brasiliensis is more virulent than other species that cause sporotrichosis like S.schenckii and results in larger, longer lasting lesion with a higher degree of local and systemic inflammation as demonstrated on mice.

[10] In addition, the treatment of felines is particularly difficult as care requires prolonged intervals of time daily and many cats fail to respond well to therapies.

[7][11] Due to this the recurence of disease can typically occur with higher severity while increasing the chances of antifungal resistance strain development.

Cutaneous lesions caused by sporotrichosis on cat's paw
Structure of itraconazole