The Spyckerscher See and Mittelsee Nature Reserve (German: Naturschutzgebiet Spyckerscher See[1] und Mittelsee) is a nature reserve in the German state of Mecklenburg-Vorpommern.
Neighbouring villages are Glowe in the northwest and Spyker in the east.
Its conservation aim is the preservation of a very attractive section of the North Rügen Bodden, a lagoon landscape which is a habitat for numerous animal and plant species.
The reserve borders immediately on the Großer Jasmunder Bodden.
The reserve is protected under EU law as part of the Nordrügensche Boddenlandschaft Special Area of Conservation[2] and the Binnenbodden von Rügen Special Protection Area[3] The reserve is in good condition thanks to the cessation of human activities.