The men's singles squash event of the 2015 Pan American Games was held from July 11–13 at the Exhibition Centre in Toronto.

[1] The Pan American Games champion is Miguel Rodríguez of Colombia successfully defended his title.

The athletes were drawn into elimination stage draw.

An athlete who lost a match was no longer able to compete.

If the score became 10-all, the side which gained a two-point lead first, won that game.