The Sri Lanka cricket team toured Bangladesh in May 2021 to play three One Day International (ODI) matches.

[3] The ODI series formed part of the inaugural 2020–2023 ICC Cricket World Cup Super League.

[8] Ahead of the tour, Kusal Perera was appointed as Sri Lanka's new ODI captain,[9] replacing Dimuth Karunaratne.

[14] On 1 May 2021, Bangladesh named a preliminary squad of 23 players to begin training ahead of the series.

[17] Rubel Hossain and Hasan Mahmud, who were both named in the preliminary squad,[18] were later ruled out of the ODI matches due to injuries.