Built in the late nineteenth century, it remains the home of an active parish, and it has been designated a historic site because of its well-preserved architecture.

Local Catholics began to purchase large amounts of land in Cathagena from black people in 1856; the parish grew strong enough to establish a school and a cemetery in 1860,[2]: 230  and St. Aloysius' Church was canonically erected in 1865.

[4] Under the pastorate of Gregory Jüssel, the church was greatly modified in the summer of 1905; only the tower and three of the walls remain from the original structure.

Built of brick, laid in a stretcher bond, the walls rest on a foundation of stone rubble from Piqua, which includes a basement.

The middle of 1905 saw the completion of a wide range of alterations,[2]: 230  including the removal of the original interior, the addition of a sacristy, the placement of the present stained glass windows, and the expansion of the sanctuary.

[5]: 2  Furthermore, Anton DeCurtins's commission to design the church at Carthagena, where he lived, led to similar requests from many other parishes: the churches of the third generation, built between 1885 and 1905, were characteristically large brick High Gothic Revival structures, dominated by tall towers, and designed by Anton or his sons.

In order to better serve the parish school, a house was erected for the nuns who taught there after they left the seminary building.