The surviving structures date to 1909 and are contributing properties of the Grand Coteau Historic District.

The earliest effort to introduce the Society of Jesus to the area came in 1826, when Louis William Valentine Dubourg, the Bishop of Louisiana and the Two Floridas, offered an estate in Opelousas, Louisiana to the Jesuit priest Van Quickenborne for use by a group of novices from the Jesuits' Maryland province.

[3] When the superior met the French party upon their arrival in New Orleans, they unanimously agreed that it would be better to establish their school in Grand Coteau, as the Iberville site would be too small to accommodate the school, was located too close to the eroding banks of the Mississippi River, and restoration of the building would be prohibitively expensive.

[5] Bishop Blanc was in attendance at the ceremonial groundbreaking on the new St. Charles College or a boarding school in Grand Coteau on July 31, 1837.

[8] While many supported the establishment of a Jesuit school in Grand Coteau, some sent letters threatening harm if they did not leave, incited by a local newspaper that opposed the move.

In response, the lay parishioners of St. Charles Church took up arms and stood watch twenty-four hours a day to guard the school and the priests.

Point's administration of the college proved to be dissatisfactory,[11] and he was relieved of office by the Jesuit superiors in 1840.