St. Joseph is an unincorporated community and census-designated place (CDP) in the town of Greenfield, La Crosse County, Wisconsin, United States.

[2] St. Joseph is in southern La Crosse County, in the northeast part of the town of Greenfield.

To the north, St. Joseph Coulee leads to Bostwick Creek, a west-flowing tributary of the La Crosse River, which joins the Mississippi at La Crosse.

The Franciscan Sisters of Perpetual Adoration have their retirement home in St.

This article about a location in La Crosse County, Wisconsin is a stub.