The University campus is located in Mengo, Rubaga Division, in Kampala, Uganda's largest city and capital.

The university campus sits on 11 acres (4.5 ha) of land and is located near Kabaka's Lake, in Mengo, close to the main Lubiri (Palace of the Kabaka of Buganda), 3 kilometres (1.9 mi) west of the central business district of Kampala.

The coordinates of the main campus are 0° 18' 6.00"N, 32° 33' 43.00"E (Latitude:0.301667; Longitude: 32.561945).

The University took in the first class of students in September 2007.

[4] St. Lawrence University is composed of five faculties:[5] The following courses are offered at the University: