After a passer-by rang the bell of the adjoining rectory, two priests hurriedly dressed and rushed into the church, saving the Host and Chalice at the altar, and vestments from the vestry.

Firemen succeeded in saving a costly stained glass window in the rear of the church, and also managed to remove several pieces of statuary, but the altar was entirely destroyed.

[5] On the evening of June 15, 1997, another major fire, believed to have started in the sacristy, devastated the century-old church, burning the slate roof and gutting the sanctuary.

The organ and its pipes were ruined, and the painting of Our Lady of Guadalupe, donated to the Hispanic parishioners who succeeded the parish's Italian and Irish immigrants, was lost.

The church was rebuilt exactly as before, with a few improvements: the original high ceiling, covered in a previous renovation, was opened, and new stained-glass dormer windows were installed in the roof, depicting the Holy Family, SS.

Along with the outer church walls, the original stained-glass windows were saved, and the marble reredos, the pulpit, and statues were restored.

Burke, under the leadership of Mother Jerome Oliver, OSU, began the school on the Feast of the Nativity of Our Lady, September 8, 1913.