St. Thomas of Villanova Catholic Secondary School is a publicly funded high school in LaSalle, Ontario, Canada.

It is operated by the Windsor-Essex Catholic District School Board and serves as the primary Catholic secondary school in the LaSalle, Amherstburg, and River Canard areas of Essex County.

[2] Villanova's Men's Baseball team has captured numerous titles at both the OFSAA-level and MHSAA-level.

The school also offers other sports teams, including football, wrestling, soccer, volleyball, basketball, swimming, many of which compete at the provincial level.

The Vocal, Drama, and Music programs collaboratively put on productions annually.