St. Vincent Hospital was created in 1888 by the Third Order of Saint Francis.

[3] The first hospital was in a home on Quincy Street in Green Bay, Wisconsin, and consisted of just one chair, four beds, and a kettle for laundry.

[3] In 1957, a large, modern addition opened, enlarging the hospital to 437 beds.

[3] In 1998, the hospital partnered with Bellin Health and County Rescue Services to construct a helipad and purchase a rescue helicopter named EAGLE III.

[4][5] In 2016, St. Vincent became the first hospital in Wisconsin to begin offering a Bioresorbable stent.