The club plays in the AFL Women's (AFLW), and is associated with the St Kilda men's team.

In September 2017, the club was granted a license by the AFL to compete in the league from the start of the 2020 season.

A team known as the "Southern Saints" participated in the league between 2018 and 2024, originally being co-managed by both clubs before the license was taken over by Sandringham in 2020.

[3] On 18 February 2017, the Australian Football League (AFL) announced the creation of a women's competition the following year.

[5] Following the successful completion of the inaugural AFLW season in 2017, the AFL launched a second round of bidding for licenses to enter the competition from 2019 onwards.