Stagecoach Merseyside and South Lancashire can trace its origins to the purchase of both Ribble Motor Services in 1988 from the National Bus Company and Glenvale Transport in 2005.

[8] This also coincided with the delivery of ten Enviro400 MMCs built with similarly high-specification interiors on Scania N250UD chassis for the Liverpool-Southport-Preston X2 express service.

[9] Further Gold buses were transferred from other Stagecoach divisions in January 2019 in order to upgrade service 38 between Kirkham and Eastham to the specification.

[14] Following the sale, Stagecoach immediately invested £6.5 million in new buses to reduce the age profile of the elderly Glenvale fleet.

Operations transferred to Stagecoach Merseyside and South Lancashire's Gillmoss depot on 9 July,[17][18] with a second iteration of Peoplesbus returning to Merseytravel contracts in January 2024.

In September 2015, Stagecoach were awarded by the council to continue running the service from July 2016 until 2021, with branded Wright Eclipse Urban bodied Volvo B7RLEs acquired from First replaced with twelve new Alexander Dennis Enviro200 MMCs following the start of the contract.

[23] As of August 2024, Stagecoach Merseyside and South Lancashire operates a fleet of 380 buses from five depots in Chester, Chorley, Gillmoss in Liverpool, Preston and the Wirral Peninsula.