It was established in 1950, in the Soviet style of territorial organization, and was named after Joseph Stalin.

[1][2][3] In 1950, the capital of the region was Orașul Stalin (Stalin City, now Brașov) and its territory comprised an area similar to what are nowadays the eastern part of Brașov County, together with Covasna County and part of Harghita County.

Initially, the Stalin Region comprised 6 raions: Ciuc, Odorhei, Racoș, Sfântu Gheorghe, Stalin, and Târgu Secuiesc.

[1][3] In 1952, the Ciuc, Odorhei, Sfântu Gheorghe, and Târgu Secuiesc raions were transferred to the newly established Magyar Autonomous Region,[4] while the raions Sibiu, Făgăraș, Mediaș, Agnita, Sighișoara, and Târnăveni were included in the Stalin Region.

Some areas in the Magyar Autonomous Region reverted to the Brașov Region, which after 1960 comprised the following raions: Agnita, Făgăraș, Mediaș, Rupea, Sfântu Gheorghe, Sibiu, Sighișoara, and Târgu Secuiesc.