Stavroupoli (Greek: Σταυρούπολη) is a village and a former municipality in the Xanthi regional unit, East Macedonia and Thrace, Greece.

Stavroupoli and Nestos Valley (Greek: Κοιλάδα του Νέστου) including Nestos River Tempi (Greek: Τέμπη του Νέστου) is a popular tour region and vacation target in North Greece.

During the Bulgarian administration of the region in World War II from 1941 to 1944, the village was infamous as the location of the Krastopole or Enikyoy concentration camp where Bulgarian Communist Party and other left-wing enemies of the ruling regime were interned.

[4] Under Ottoman rule, the Ottoman Turkish name of the village was يڭى كوى Yeni Köy (in Greek, Γενή Κιόι, in Bulgarian Еникьой Enikyoy) 'New Village'.

Its name was Hellenized as Greek: Σταυρούπολις, romanized: Stavroupolis, lit.