Moore's columns have appeared in outlets such as the Wall Street Journal, The Washington Times, The Weekly Standard and National Review.

Along with Larry Kudlow, Moore advised the Trump administration during the writing and passage of the Tax Cuts and Jobs Act.

[4][5] As senior economist of the U.S. Congress Joint Economic Committee under Chairman Dick Armey of Texas, Moore was said to be "instrumental in creating the FairTax proposal".

[4] In 1999, Moore co-founded and became president of the Club for Growth, a group advocating tax cuts and a reduction in government spending, along with supporting political candidates who favored free-market economic policies.

After Moore's departure, lawyers for the group sent letters to him and members of his new organization, the Free Enterprise Fund, threatening legal action for allegedly stealing the group's mailing list to raise funds for his new organization; Moore's partner Mallory Factor stated the list was acquired elsewhere.

[12] In May 2015, Moore co-founded the advocacy group Committee to Unleash Prosperity with Laffer, Larry Kudlow, and Steve Forbes.

"[16][17] In 2017, Moore worked with Larry Kudlow on overhauling the US tax policy for the Trump administration, which was eventually passed into law by Congress.

Miriam Pepper, editorial page editor for the Star stated "I won't be running anything else from Stephen Moore.

"[31][32] In a 2014 op-ed in the Washington Times, Moore cited the role of a "culture of virtue" in America's economic success, writing, "What is irrefutable is that marriage with a devoted husband and wife in the home is a far better social program than food stamps, Medicaid, public housing or even all of them combined.

[41] In the book, Moore and Laffer argue that the Trump administration's 2017 tax plan would raise GDP growth rates to as much as 6% and not increase budget deficits.

"[39][42] Moore asserted in a December 2018 appearance on CNN that the Federal Reserve was causing deflation in the economy, although Commerce Department data showed there was consistent inflation.

[46][45] In September 2018, Moore wrote a Wall Street Journal opinion piece entitled, "The Corporate Tax Cut Is Paying for Itself," in which he asserted that "faster-than-expected growth has produced a revenue windfall."

[14] On March 13, 2019, Moore co-authored a column in the Wall Street Journal which asserted that the Federal Reserve's policies were slowing the economy and causing "wild swings in the stock market," at a time the Dow was up 13% for the year.

Larry Kudlow, the Director of the U.S. National Economic Council, showed the article to President Trump, who decided he wanted to place Moore on the Federal Reserve Board.

"[55] In 2023, Moore co-authored the chapter on the Department of the Treasury in the Heritage Foundation's Project 2025 book, Mandate for Leadership: The Conservative Promise.

[58][14] After the nomination was announced, Moore stated "I’m kind of new to this game, frankly, so I’m going to be on a steep learning curve myself about how the Fed operates, how the Federal Reserve makes it decisions, and this is a real, exciting opportunity for me.

[71] In April 2019, 105 professors, former government officials, and analysts signed a one-sentence letter expressing support for Moore's candidacy for the Federal Reserve Board.

Signatories included Steve Forbes, Ed Feulner, and Bill Ford, the former President of the Federal Reserve Bank of Atlanta.

[72] Endorsements for Moore's nomination also came from his long-time collaborator Larry Kudlow, who recommended the appointment,[43] and from Adam Brandon, president of the conservative advocacy group FreedomWorks.

[73] In an appearance on Fox Business Network, political commentator Charlie Gasparino described Steve Moore as "the counterweight to [Chair of the Federal Reserve Jerome] Powell’s hawkishness.

Following his withdrawal, Moore penned an op-ed in the Wall Street Journal where he decried his critics, writing, "What did me in was not my economic ideas but gutter campaign tactics and personal assaults.

"[80] Some Senate Republicans expressed relief that they would not have to cast a vote for or against him, because of his history of remarks deprecating women as well as a concern that he would not be independent of the White House.

Additionally, Moore became chief economic officer of Frax, a cryptocurrency company that branded itself "the world’s decentralized central bank.