[6] At the age of 17, while a junior in high school, Sui He entered a Chinese modeling contest and won.

Her breakthrough season was Fall/Winter 2011, where she most notably opened for Ralph Lauren and opened and closed Vivienne Tam in New York, walked for Dolce & Gabbana in Milan and walked exclusively for Shiatzy Chen and Dries van Noten in Paris.

[10] Other ready-to-wear show appearances include Chanel, Dior, Helmut Lang, Hermes, Hervé Léger, Jean Paul Gaultier, Missoni, Mugler, Oscar de la Renta, Ralph Lauren, and Y-3.

[11] Other covers include i-D and V.[11] In 2012, Sui He was selected to be the first Asian global spokesmodel for Shiseido.

[11] Most recently, Sui He appeared in the Printemps with Dior Holiday 2012 campaign along with Carolyn Murphy which was styled by Carine Roitfeld and photographed by Mario Testino.