NEO is the first Super Robot Wars title to appear on the Wii.
NEO also stands out as the many anime series featured were shows aimed at a younger audience, three of the titles making a debut: Haō Taikei Ryū Knight, NG Knight Lamune & 40 and Shippū!
Super Robot Wars NEO introduces many new gameplay features to the Super Robot Wars franchise, such as a gridless map system, wherein movement is displayed as a radius as opposed to a number of squares on the grid.
Movement is possible in any direction, terrain barriers and blocking units notwithstanding.
Certain attacks have effects that directly influence the map: attacking all targets in a straight line while moving the attacker past them, travelling over terrain barriers to hit enemies behind them, or pushing enemies back, possibly incurring damage if they hit walls or are pushed off ledges.