His cartoons appeared in a multitude of genres, including advertising commissions for such companies as Eveready Batteries, Jell-O, OK Used Cars, S.O.S Pads, Rambler, Ralston Cereal, and more.
[5] Hoff wrote and illustrated over 60 volumes in the HarperCollins "I Can Read" series for beginning readers, most notably Sammy the Seal and the popular Danny and the Dinosaur (1958), which sold 10 million copies and has been translated into a dozen languages.
[5] Tuffy was originally commissioned by William Randolph Hearst in 1938, and was declared "essential for national morale" during the American involvement in World War II.
[7] Starting in 1933, Hoff began to contribute cartoons to leftist newspapers and magazines, including The Daily Worker and New Masses as A. Redfield, the pseudonym that he adopted for his radical work.
He was questioned by the FBI in 1952 about his A. Redfield work and Communist Party association,[7] after being photographed with Marxist civil liberties advocate Corliss Lamont at a protest against the atomic bomb the previous year.