Her major works include The Twilight of Life (1894), an oil painting in the collection of the Art Gallery of Ontario.

[5][6] Tully began her career colouring photographs and designing Christmas cards, and she worked with a variety of mediums including oil and pastel.

[7] Tully kept a studio in Toronto (from 1888 to 1890), where she taught regular classes, and participated steadily in the artistic life of the city.

[8][9] She also travelled internationally to paint and to participate in exhibitions, including sojourns in London (1895), the Netherlands (1906–08) and the Jersey Channel Islands (1906–08).

[1][10] She was elected a member of the Ontario Society of Artists in 1889, and became an Associate of the Royal Canadian Academy of Arts the same year.