TNM staging system

It is also used by the American Joint Committee on Cancer (AJCC) and the International Federation of Gynecology and Obstetrics (FIGO).

The Mx designation was removed from the 7th edition of the AJCC/UICC system, but referred to cancers that could not be evaluated for distant metastasis.

For the T, N and M parameters exist subclassifications for some cancer-types (e.g. T1a, Tis, N1i) The TNM system is used to record the anatomical extent of disease.

The Union for International Cancer Control (UICC) uses the term Stage to define the anatomical extent of disease.

The criteria used in the TNM system have varied over time, sometimes fairly substantially, according to the different editions that AJCC and UICC have released.