[5][6] The protein encoded by this gene is a member of the tripartite motif (TRIM) family.

The TRIM motif includes three zinc-binding domains, a RING, a B-box type 1 and a B-box type 2, and a coiled-coil region.

Its carboxy terminus contains an ADP-ribosylation factor domain and a guanine nucleotide binding site, while the amino terminus contains a GTPase activating protein domain which acts on the guanine nucleotide binding site.

The protein localizes to lysosomes and the Golgi apparatus.

It plays a role in the formation of intracellular transport vesicles, their movement from one compartment to another, and phospholipase D activation.