It is located right on the side of a main road in Naxxar that lead to San Pawl tat-Targa.

The farmhouse is found in the same area as the Hompesch Hunting Lodge of which both have the same public garden in front of them.

The towers served the community, including the Ta' Cisju Farmhouse, as a better defense and thus allowing the prosperity of the village.

[5] Naxxar started to develop into a village as it is known today during the British period as during the knights it was mostly an agricultural area and a hunting zone.

probably to make it a comfortable residence, but significantly the original building was maintained and restored sometimes in the early 21st-century.

[4] Ta' Cisju Farmhouse is a good example of Maltese traditional agricultural building.

It was built to serve for agricultural needs in 1730, with some possible influence of building of the order of St. John, but its description shows it is largely traditional.

The farmhouse has typical traditional characteristic similar to other farmhouses in Naxxar, such as; a wide arched doorway (remissa), small window at the first floor (the first floor is traditionally known as Għorfa), waterspouts on the exterior, limestone slabs and other.