Tabernanthalog

Tabernanthalog (TBG, DLX-007)[1] is a novel water-soluble, non-toxic azepinoindole[2] analog of the psychoactive drug Tabernanthine first synthesized by Professor David E. Olson at UC Davis.

[3] In rodents, it was found to promote structural neural plasticity, reduce drug seeking behavior, and produce antidepressant like effects.

[1][4][5][6] It has also been shown that it effectively reduces motivation for heroin and alcohol in rats.

This indicates its efficacy in animals with a history of heroin and alcohol polydrug use.

[6] Due to the rapidly-induced and enduring neuroplasticity, tabernanthalog is a member of the class of compounds known as non-hallucinogenic psychoplastogens.

Ball and Stick 3D representation of a tabernanthalog molecule
Ball and Stick 3D representation of a tabernanthalog molecule