Tachystatins are antimicrobial chitin-binding peptides from Japanese horseshoe crab.

Amino acid residues Tyr(14) and Arg(17) in Tachystatin B are thought to be the essential residues for chitin binding.

[2] These small proteins contain a cysteine-stabilised triple-stranded beta-sheet with an inhibitor cystine knot motif and show features common to membrane-interactive peptides.

Tachystatin A is thought to have an antimicrobial activity similar to defensins.

[1]