Tadzhikosuchus (also spelt Tajikosuchus) is an extinct genus of neosuchian crocodyliform from the Late Cretaceous of Tajikistan.

Three species have been named: the type species T. macrodentis, described by Efimov in 1982 from the lower Santonian-age Upper Cretaceous Ialovachsk Formation of Kansai, Tajikistan, in the Fergana Basin of Tajikistan; T. neutralis from the same location, by Efimov in 1988; and T. kizylkumensis from Turonian-age rocks of the Upper Cretaceous Bissekty Formation of Dzharakhuduk, Uzbekistan, by Nesov and colleagues in 1989.

They also could not determine how Tadzhikosuchus and the contemporaneous Zhyrasuchus were related, or even if they were synonyms, due to the poor fossils available.

To date, Tadzhikosuchus is mostly known from partial dentaries, which were initially considered to have been very similar to Prodiplocynodon (a crocodyloid) by Efimov.

However, since dentaries are not known for Prodiplocynodon, this conclusion was considered questionable by Jeremy Martin and Massimo Delfino in 2010.