Tamalameque is a town and municipality in the Colombian Department of Cesar.

Tamalameque is located on the right bank of the Magdalena River and borders Chimichagua and Pailitas in the north, Pelaya in the east, La Gloria in the south and in the west the departments of Bolívar (El Peñón) and Magdalena (El Banco).

[1] The first conquest expedition into the interior of Colombia, led by Gonzalo Jiménez de Quesada passed through Tamalameque in 1536.

[1][3] Tamalameque, situated in an area dotted with wetlands and swamps at the Magdalena River, has an economy based on fishing, agriculture and livestock farming.

Main agricultural products cultivated are rice and sorghum, and farther from the river bananas and yuca.