In 1982 she received a Bachelor of Applied Arts degree in Radio and Television Arts from Ryerson Polytechnical Institute in Toronto, Ontario; she was in the same class as science-fiction writer Robert J. Sawyer and they collaborated on their final TV Studio Lab assignment, a short science-fiction show.

From 1984 to 1992 she worked at Bakka, North America's oldest surviving science fiction book store, in Toronto.

In 1992, after living for 13 years in downtown Toronto, she moved with her four large cats to rural Ontario, where she currently resides with her wife, fellow fantasy writer Fiona Patton.

[4][5] Huff is one of the most prominent Canadian authors in the category of contemporary fantasy, a subgenre pioneered by Charles de Lint.

The CBC Television series Blood Ties was based on Huff's Vicki Nelson novels, and also aired in the United States on Lifetime.