Its collection consists primarily of the artifacts which were excavated from the Necropolis of Monterozzi to the east of the city.

Over the time the collection was enriched by the numerous finds from the ancient city of Tarquinia and the Necropolis of Monterozzi.

On the ground floor the sarcophagi, including the important Sarcophagus of Laris Pulenas, and other stone artifacts from the middle of the fourth century BC are exhibited in chronological order.

Especially pottery from Corinth was imported in large quantities from the end of the seventh to the sixth century BC and imitated by the Etruscans.

In the hall of weapons the "Cavalli Alati" are exhibited, a relief of a pair of winged horses.

They once decorated the Ara della Regina, an Etruscan temple in Tarquinia which dates to the fourth century BC.