He is best known for co-founding the production/sales company Good Machine, where he produced the first films of such filmmakers as Ang Lee, Nicole Holofcener, Todd Field, Michel Gondry, Moisés Kaufman, and Shari Springer Berman and Robert Pulcini.

Hope has also produced two Sundance Opening Night selections: Nicole Holofcener's Friends with Money (2006) and Moises Kaufman's The Laramie Project (2002), which was nominated for five Emmys.

[citation needed] In 1990, Hope and James Schamus founded Good Machine, an independent film production company based in New York.

At Good Machine, Hope and James Schamus produced Ang Lee's early films including Pushing Hands, The Wedding Banquet and Eat Drink Man Woman (both Academy Award nominees), The Ice Storm, and Ride with the Devil.

[citation needed] With fellow Good Machine producers Anne Carey and Anthony Bregman, and head of business affairs Diana Victor, Hope co-founded New York production company This is That in 2002.

[citation needed] After producing seventeen films, the company closed its doors in September 2010 citing financial struggles with maintaining the office space.

[citation needed] On January 8, 2014, Hope was named CEO of Fandor, a subscription online service for independent and international films.

[8] He left Fandor at the beginning of 2015 to become the head of production for Amazon Original Movies, stating, "To help carry the torch into the feature film world for such an innovative company is a tremendous opportunity and responsibility.

Amazon has released 38 films since 2016, notably winning three Academy Awards in the studio's first year as a distributor for titles Manchester by the Sea and The Salesman.

[citation needed] Hope was instrumental in organizing the successful 2003 antitrust campaign against the MPAA and its ban on screeners including testifying in court.