It is located approximately 100 kilometres (62 mi) southwest of the state capital Toluca, along Federal Highway 34.

Father Plancarte says in Book I of the Annals of the Museum of Michoacan that the Tecos were a group related to the Mexicas who lived in the Purépecha kingdom.

By 1476 the Aztec king Axayácatl conquered the Matlatzincas and took control of their lands including what is now Tejupilco.

After the Spanish Conquest, Andrés de Tapia was assigned to subdue the old Matlatzinca lands where he met no resistance in this area.

[3] Agriculture is the most important economic activity here, using 93,586 hectares (231,260 acres), growing corn, beans, avocados and peaches.