It connects the town of Huntland with the community of Elora.
For the majority of its length, SR 122 is known as John Hunter Highway.
It heads northeast as John Hunter Highway through farmland and rural countryside for several miles to cross into Franklin County.
The highway turns north along Main Street and passes by several homes and businesses to come to an end at an intersection with US 64/SR 15.
The entire route of SR 122 is a two-lane highway.