In structural biology, ternary complex can also be used to describe a crystal containing a protein with two small molecules bound, such as a cofactor and a substrate; or a complex formed between two proteins and a single substrate.
This is seen in multi-substrate enzyme-catalyzed reactions where two substrates and two products can be formed.
The ternary complex is an intermediate species in this type of enzyme-catalyzed reaction.
[3] The term ternary complex can also refer to a polymer formed by electrostatic interactions.
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