Tetramethylthiuram sulfide is an organosulfur compound with the formula ((CH3)2NCS)2S.

It is a yellow solid that is soluble in organic solvents.

It is the parent member of a large class of tetraalkylthiuram sulfides.

[1] It is used as an activator in the sulfur vulcanization of natural and butyl rubbers.

[2] It is prepared by desulfuration of tetramethylthiuram disulfides with triphenylphosphine or cyanide: According to X-ray crystallography, the molecule consists of two planar (CH3)2NCS subunits joined by a sulfide.