Tetraphenylethene (TPE) is an organic chemical compound with the formula Ph2C=CPh2, where Ph = phenyl (C6H5).

It has been described as a yellow solid, but single crystals are colorless.

The molecule is crowded such that all four phenyl groups are twisted out of the plane defined by the center six carbon atoms.

[3] Tetraphenylethene is used as a precursor to other organic compounds, often in the area of supramolecular chemistry.

Tetraphenylethene can be synthesized from diphenyldichloromethane.