[2] Texas County comprises the Guymon, OK Micropolitan Statistical Area.

The county economy is largely based on farming and cattle production.

When the formation of the county was authorized by the Constitutional Convention of 1907, the county was so named because it was wholly included within the limits of the Texas Cession of 1850, whereby the ownership of the area was passed from the State of Texas to the United States government.

From 1850 to 1890, its lands were never attached to any state or territory, never surveyed, and never divided into townships and sections like the eastern counties were.

Tributaries of the river are Coldwater, Hackberry, Goff, Teepee, and Pony Creeks.

42.0% of the population were Hispanic or Latino of any race (34.3% Mexican, 3.5% Guatemalan, 0.7% Cuban, 0.7% Spanish).

21.20% of all households were made up of individuals, and 8.20% had someone living alone who was 65 years of age or older.

The county remains the nation's largest producer of natural gas.

The 2000 MW Windcatcher wind farm project, consisting of 800 wind turbines from GE and a high voltage AC power line, was proposed for Texas County and adjacent Cimarron County, but ran into opposition and was finally cancelled in July 2018.

In 1921, the legislature changed the name to Panhandle Agricultural and Mechanical College and authorized the school to offer a two-year curriculum.

Guymon Municipal Airport is a city-owned, public-use airport located two nautical miles (3.7 km) west of the central business district of City of Guymon in Texas County.

The following are included among the twenty-four sites in Texas County listed on the National Register of Historic Places[21]