The highway heads east along Pecan Boulevard through Mission to an intersection with SH 107 (Conway Avenue).

As it enters Pharr, the highway passes under I-69C/US 281, intersecting the freeway's frontage roads.

The highway continues east, leaving Alamo, to its eastern terminus at FM 1423 (Val Verde Road).

On December 17, 1952, the route was extended west to SH 107 on the north side of Mission.

The route was redesignated SH 495 on January 23, 2001, and was extended westward to Abram Road to make a new connection with US 83; one section was transferred to SH 364.The entire route is in Hidalgo County.