The team takes on the case of an ailing groom-to-be (guest star Adam Garcia) named Ted.
Thirteen and Taub check where Ted lived before he moved into his fiancée's room, but the owner comes back and sees them.
The team comes in to prep Ted for his angio, but every time he sits up he faints, and he stabilizes when he lies down.
House thinks it could be postural orthostatic tachycardia syndrome (POTS), causing his blood pressure to plummet when he's upright.
House thinks the spinal tap caused Ted to spring a leak, worsening the headaches.
Taub suggests that arterial disease causing acute ischemia could explain the heart, neurological symptoms, and possibly even POTS.
The test shows everything's normal with his penis' blood flow, but Ted starts to lactate.
Ted's therapy caused his brain to swell just enough to plug the opening, cutting off his CSF.
She states that she wants to be friends, and House retorts, as the closing remark, that it is the last thing he wants, with the unspoken suggestion that he wants more.
The last scene involves House stroking his leg in pain, glancing at ibuprofen before deciding to pull a bottle of alcohol from his desk and drinking.
Greg House is at his absolute best when he's firing out acerbic one liners like a sniper with a machine gun full of sarcasm bullets..." but also noted that the sixth season had suffered slightly and that this particular episode redeemed it.
The patient-of-the-week story arc was well plotted out and the diagnosis felt justified, albeit cruel.