[1] The book featured impressions of life in outer space by a number of artists including Don Davis, Rick Guidice, and Chesley Bonestell.

Many of the concepts illustrated in The High Frontier can be seen in the early series of the anime franchise Mobile Suit Gundam, which depicts a world where humans have migrated into space colonies.

[2] The O'Neill cylinder colony design appears frequently, largely unchanged from its original concept, such as in Policenauts.

The main space station in the popular TV series, Babylon 5, is similar to an O'Neill cylinder, but with internal lighting replacing the windows and mirrors.

Science fiction writer Charles Stross wrote a critical essay with a similar title on the feasibility of interstellar space travel and making practical use of various moons and planets in the Solar System: The High Frontier: Redux.