The Road Runner Show is an American Saturday morning animated anthology series which compiled theatrical Wile E. Coyote and the Road Runner cartoons from the Looney Tunes and Merrie Melodies, which were produced by Warner Bros. Cartoons between 1949 and 1964.

DePatie–Freleng Enterprises provided the animation for the show's intro, closing credits as well as the wrap-around bumpers.

[6] Each show would feature one Road Runner/Coyote cartoon, with a Tweety and Sylvester cartoon in the middle segment, and other WB animated character(s) in the third segment (usually Elmer Fudd, Foghorn Leghorn, Speedy Gonzales, Pepé Le Pew and Hippety Hopper).

The intro of every cartoon was replaced with a simple title card, along with the shortened version of William Lava's arrangement of "The Merry-Go-Round Broke Down".

An instrumental version was used as the theme song for the Road Runner and Wile E. Coyote segments of The Looney Tunes Show.