Thelephoric acid is a terphenylquinone pigment that is found in several fungi, such as Omphalotus subilludens[1] and Polyozellus multiplex.

[2] Thelephoric acid has been shown to inhibit prolyl endopeptidase, an enzyme that has a role in processing proteins (specifically, amyloid precursor protein) in Alzheimer's disease.

Chemicals that inhibit prolyl endopeptidase have attracted research interest due to their potential therapeutic effects.

[3][4] It is derived from atromentin, and its precursor can be from cyclovariegatin.

Fragmentation patterns have suggested that polymers of thelephoric acid exists.