[citation needed] The severe symptoms are cardiac arrhythmias,[5] epileptic seizures, internal bleeding, heart attacks, and eventually death.
[citation needed] Median lethal (LD50) doses of theobromine have only been published for cats, dogs, rats, and mice; these differ by a factor of 6 across species.
[12] Medical treatment performed by a veterinarian involves inducing vomiting within two hours of ingestion and administration of benzodiazepines or barbiturates for seizures, antiarrhythmics for heart arrhythmias, and fluid diuresis.
Theobromine is also suspected to induce right atrial cardiomyopathy after long term exposure at levels equivalent to approximately 15 g/kg (0.24 oz/lb) of dark chocolate per day.
A necropsy and toxicology report performed at the University of New Hampshire in 2015 confirmed they died of heart failure caused by theobromine after they consumed 41 kg (90 lb) of chocolate and doughnuts placed at the site as bait.