It features a little boy talking about the strange creatures that live in his house, such as the yeps on the steps, the nooth grush on his toothbrush, the wasket in his basket, the zamp in a lamp, the yottle in the bottle, and the Nureau in the bureau.

He describes creatures that he likes, such as the Yot in the pot, the Zable on the table, the Ghair under the chair, some Nupboards in cupboards, some Yeps on steps through the stairway, and the Zillow on the pillow.

He also describes creatures that he doesn't like, such as the Yottle in the bottle, the Bofa on the sofa, the Nooth Grush on his toothbrush, the Vug underneath the rug, the Quimney up the chimney, and the Zall past the hallway.

four out of five stars, praising the illustrations for their color palette and for their use as visual aids when reading more difficult words.

[10] Elizabeth B. Moje and Woan-Ru Shyu described it as one of Seuss's "most language-conscious works", saying that it allowed for children to engage with language using humor.

[12] The book's ending demonstrates a common Dr. Seuss theme of independence and self-confidence, as the boy says he is happy with his situation regardless of whether the reader believes him or not.

was adapted as a read-and-learn mobile app by Oceanhouse Media, including a digital copy of the book and ten educational minigames.